\documentclass{jarticle}
\usepackage{color}
\usepackage{array}

\begin{document}

\newcolumntype{C}{>{\itshape}c}
\newcolumntype{L}{>{\bfseries}l}
\newcolumntype{R}{>{\color{red}}r}
\newcolumntype{C}{>{\itshape}c}
\newcolumntype{D}{>{\color{blue}\itshape}r@{\color{blue}\itshape.}>{\color{blue}\itshape}l}

\begin{tabular}[c]{|C|L|R|D|}
  \hline
  300.30 & 12.00 & 13.00 & 1223&45\\
  40.30  & 14.56 & 3544.20 & 223&45\\
  40.30  & 14.56 & text & 56&70\\
  \hline
\end{tabular}

\end{document}
